Pharmaceutical forms present on the market

The pharmaceutical forms of  Bisolvon®  listed below are authorized for sale in Italy by the Ministry of Health:

• Bisolvon® 8 mg in tablets in packs of 20 tablets: price 7.50 euros;
• Bisolvon® 8 mg in soluble tablets in packs of 16 tablets: price 7.90 euros;
• Bisolvon® 2 mg/mL in oral solution in 40 ml bottle: price 8.90 euros;
• Bisolvon® 4 mg/2 mL in injectable solution in packs of 5 vials: price €8.77;
• Bisolvon®, 8 mg/5 ml, syrup, 250 mL bottle: price 9.90 euros.

To purchase all the pharmaceutical forms of Bisolvon® it is not necessary to have a medical prescription except for the vials which instead need a repeatable medical prescription.

How does it work?

Bisolvon® is a medicine that belongs to the category of mucolytics which have the purpose of thinning the mucus by reducing the typical symptoms of wet cough. Bromhexine hydrochloride, the active ingredient of this drug, is used as it manages to act by thinning the mucus and reducing cough symptoms. The drug has a secretolytic and secretomotor action at the bronchial level which helps to promote expectoration and at the same time relieves cough.

Posology and Method of Use

The methods and quantities of intake recommended for Bisolvon® are as follows.

Bisolvon® tablets in adults and adolescents over 12 years: 2 tablets 3 times a day. In children aged 6 to 12 the dose is: 1 tablet 3 times a day. In children aged 2 to 6 years: we recommend ½ tablet 2 times a day.

Bisolvon® soluble tablets the dosage is as follows. In adults and adolescents over 12 years it is: 1 tablet 3 times a day. The tablets dissolve quickly and the solution should be mixed and drunk immediately.

For Bisolvon® oral solution in drops , the dosage is as follows: in adults and adolescents over 12 years of age 8 mL of drug three times a day. In children aged 6 to 12 years 2-4 mL three times a day. In children from 2 to 6 years of age 20-40 drops three times a day.

Bisolvon® solution for injection one vial to be injected intramuscularly or slowly intravenously 2 or 3 times a day.

Bisolvon® 250 mL bottle in adults: 5-10 mL three times a day. In children older than 2 years: 2.5/5 ml three times a day. It is recommended to take the drug after meals. The dose can be measured with the special measuring cup supplied.

For patients suffering from renal insufficiency and for patients suffering from hepatic insufficiency the dose should be advised by the doctor. There are no particular indications, but it is still good practice to consult your doctor.

Overdose

At the moment there have not been sufficient studies on the overdose of the drug Bisolvon® . At present, the symptoms of an overdose are not known, but it is still advisable to consult your doctor if you think you have taken too much of the drug. For any doubts on the use of the drug Bisolvon® and on a possible overdose, it is advisable to seek the advice of your doctor or trusted pharmacist.

Can it be taken during pregnancy and breastfeeding?

For the use of Bisolvon® during pregnancy and lactation, refer to the doctor’s instructions. Do not take any medications if you are pregnant or breastfeeding, including over-the-counter medications, without first consulting your doctor.

At the moment there are not sufficient studies on the toxicity of this drug on the fetus or infant, but it is still advisable not to take the drug during pregnancy or breastfeeding. During pregnancy or breastfeeding, drugs should only be taken under strict medical supervision and only if the benefits outweigh the risks.

Contraindications

The use of Bisolvon® is contraindicated in the case of overt hypersensitivity to bromhexine hydrochloride or to any of the excipients present in the drug. Bisolvon® tablets contain lactose and therefore it is necessary to avoid taking them. Intolerant individuals should take the drug with caution.

At the moment there are no known contraindications of the drug, but it is advisable to consult your doctor in case of any doubts.

Interaction with other drugs

At the moment there are no known interactions with other drugs, but it is still advisable to notify your doctor if you are taking, will have to take or have taken other drugs at the same time as Bisolvon®-based therapy.

Side effects

There are currently no known side effects related to the consumption of Bisolvon® at recommended dosages. If the patient notices any side effects not listed in the leaflet, he must consult the doctor or pharmacist who will notify the Italian Medicines Agency and communicate the hitherto unknown side effects.