How much?

The following pharmaceutical forms are authorized for marketing in Italy:

• Tetramil® 0.3+0.05% in a 10 mL bottle at a price of 8.81 euros;
• Tetramil® 0.3+0.05% in single-dose vials in packs of 10 of 0.5 mL at a cost of 10.13 euros.

How does it work?

The drug Tetramil® acts through two specific actions: decongestant and antihistamine. Tetryzoline and pheniramine are the active ingredients which perform two different actions on the eye. The first is a vasoconstrictor that aims to reduce the inflammation and edema present, while the second is an antihistamine that works by blocking the histamine H1 receptors.

Dosage: how is it used?

As far as the dosage is concerned, it is necessary to comply with the following as well as with the information provided by the doctor or contained in the package leaflet. Instill in the eye affected by the allergy 1 or 2 drops 2 or 3 times a day. Never exceed the recommended doses.

A higher dosage of the product than indicated can give rise to severe systemic effects. The single-dose vial should not be reused because it does not contain preservatives while the multidose vial can be stored and reused.

For patients suffering from renal insufficiency and in the case of patients with hepatic insufficiency, there are no particular precautions to be taken. For any doubts about the drug and its dosage, it is advisable to consult your trusted doctor.

Store the product in a cool, dry place away from sources of direct light and heat.

Overdose

Studies have been carried out for an overdose of Tetramil®. The medicine can cause toxic phenomena at high doses. Accidental ingestion can cause a reduction in the activity of the nervous system which can cause marked sedation and coma.

Do not take a double dose of medication to make up for a forgotten dose, as taking a double dose could increase the risk of overdose .

Can it be taken during pregnancy?

With regard to the possibility of using Tetramil® during pregnancy and breastfeeding, you need to ask your doctor’s opinion. The drug is contraindicated in pregnancy and breastfeeding.

If you are pregnant , think you are pregnant or are planning to become pregnant, you should ask your doctor or pharmacist for help before starting therapy with this medicinal product. During pregnancy and breastfeeding, no drug or supplement should be used without first seeking medical advice.

Even simple over-the-counter drugs or supplements that may seem completely harmless can cause significant damage to the fetus or infant. For any doubts about the drug and its use in pregnancy and breastfeeding, it is advisable to consult your doctor.

Contraindications

The use of tetrizoline and pheniramine is not recommended in cases of hypersensitivity to the same, as well as in cases of hypersensitivity to the excipients contained in the drug. The excipients contained in the drug are:

• For the multidose bottle: boric acid, sodium ethylmercurythiosalicylate, borax, sodium carboxymethylcellulose and water for injections;
• For the single-dose container: boric acid, water for injections and borax;

The drug is contraindicated if the patient is allergic to nasal decongestant medicines, glaucoma and serious eye diseases. If the patient is taking drugs belonging to the class of monoamine oxidase inhibitors, he should take Tetramil® with caution.

The drug is contraindicated in children under 12 years of age. For any doubts about the drug and its possible contraindications, it is advisable to consult your doctor.

Interaction with other drugs

Tell your doctor if you are taking, have taken or will be taking any other medicines together with Tetramil®. The drug can interact with medicines belonging to the class of monoamine oxidase inhibitors because it can cause an increase in blood pressure.

For any doubts about the drug and its possible interactions with other medicines, it is advisable to consult your doctor or pharmacist.

Paying attention to the instructions of your doctor, your pharmacist or those given in the package leaflet reduces the risk of suffering the damage of possible interactions.

Side effects

This medicine, like all other medicines, can also cause side effects, although not everyone gets them. You may experience allergic reactions and effects affecting the eye such as dilation of the pupil and even increased pressure in the eye.

The drug could cause among the side effects :

• Increased blood pressure;
• Headache;
• Nausea;
• Increased blood sugar levels;
• Drowsiness;
• Hypotonia.

If the patient notices side effects, he should consult his doctor. If you notice hitherto unknown side effects, you must report them to your doctor or pharmacist or via the form on the official website of the Italian Medicines Agency.

Reporting side effects associated with the drug can help improve awareness of the drug and learn more about the safety of the drug. For any doubts about the drug and its possible side effects, it is advisable to consult your doctor.

Paying attention to the instructions of the doctor, pharmacist or package leaflet reduces the risk of incurring unpleasant side effects related to the use of the drug. The product does not cause driving problems and does not interfere with the use of machines.